The ultimate sacred purpose of our work is to make the link between the dramatic picture of the affected individual who is the patient as a human macro-entity, and the patient as a molecular biological micro-entity. The next feat is the prevention or correction of the molecular malady through personalized medicine. This Vision will be accomplished by achieving excellence in three directions, those being front line innovative clinical and laboratory research, continuous education and training of all scientific personnel and continuous improvement of medical care to patients by medical and nursing personnel.
We, the people at the Molecular Medicine Research Center, aspire to create an upgraded research environment with the necessary tools for innovative front line research in the field of kidney diseases and molecular medicine. With the combination of clinical and laboratory medicine focused on nephrogenetics, MMRC offers expertise in research instruments that include population genetics and biostatistics, bioinformatics, molecular and cell biology, as useful tools for studying and better understanding of inherited or genetically influenced diseases such as chronic kidney disease and diabetic nephropathy. At MMRC we care about improving human health, through promoting research, innovation and education, in a patient-centric approach.
|Schematic presentation of the Mission Statement of MMRC|
General Information - The Research Program
The Molecular Medicine Research Center (MMRC) was created as a result of external competitive funding secured by the Coordinator and his colleagues, in the form of an infrastructure Strategic Program. The program was co-funded by the Regional Development Fund of the European Union and the Republic of Cyprus through the Cyprus Research Promotion Foundation, with a total of 2mi euro and included the creation of the first Biobank in the country. This project was ranked first among 42 applications, in a 2-phase procedure. The Biobank was approved by the Cyprus National Bioethics Committee in 2011 to operate for the next 25 years.
The research activities of MMRC are quite diverse with a focus on inherited renal conditions, while the approved Biobank is for archiving data and biological material of patients with all diseases with a genetic component, either of monogenic Mendelian inheritance or complex multifactorial aetiology. It aims at the development and maintenance of a research unit focusing on the improvement of human health, through promoting research, innovation and education, in a patient-centric approach.
Fields of activities of the MMRC are the following:
1. Development of the first Cyprus Biobank for collecting and archiving data and biological material from volunteers regardless of age, sex, religion, language, ethnicity or community origin. The data and material are available to the entire research and medical community in Cyprus while collaborations with colleagues abroad are being pursued and under development.
2. Research in human molecular and medical genetics. With the use of the Biobank material and material that was collected during previous years, research programs are developed in the areas of heritable diseases or diseases where the genetic component plays a significant role for the presentation of symptoms (for example chronic kidney disease, diabetes and diabetic nephropathy, coronary artery disease, among many). Translational research is at the forefront of its activities, incorporating expertise and know-how from many collaborators in Cyprus and abroad, while an effort is made to motivate more clinicians in to research. Also, a long term goal is the comprehensive in-depth investigation of the genetic heritage of Cypriots.
3. Development of new and novel molecular diagnostics tests as a result of the research being developed at MMRC. New genetic DNA markers and mutations are being sought and identified that are responsible for the inheritance of monogenic disorders or even multifactorial conditions with significant genetic contribution. These findings provide easier and more robust diagnosis of patients and relatives, and contribute to disease prevention.